卒中后痉挛相关生物标志物的研究进展 

区家源^一作 朱美英^一作 张建博^二作 苏浩强^三作 吕政^通讯作者 

广东省深圳市龙岗中心医院，518000；

摘要：卒中后痉挛（PSS）作为脑卒中后常见的并发症，其确切定义及机制至今尚未充分揭示，同时也因动物实验研究的匮乏，PSS相关生物标志物的确立面临重大挑战。因此，探讨PSS相关生物标志物，在寻找有效治疗PSS的途径上具有极其重要的作用。本综述旨在从GABA-Glu能系统、氯离子稳态以及BDNF-TrkB方面入手，深入探讨PSS的相关生物标志物，通过揭示其相关性，尝试整理其在PSS研究中的作用，为研究PSS提供参考。

关键字：卒中后痉挛；GABA；Glu；氯离子稳态；BDNF-TrkB；KCC2 

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