间接测热法在脓毒症患者能量代谢的研究进展
刘远星1，2 王茹1,2 黄鑫1,2 金艺华1 侯志凌1（通讯作者）

1佳木斯大学临床医学院，黑龙江佳木斯，154000；

2佳木斯大学附属第一医院急诊科，黑龙江佳木斯，154000；

摘要：据2016年第三次国际会议共识，脓毒症定义为“宿主对感染反应失调引起的危及生命的器官功能障碍”，新定义相比旧定义，不仅阐明了脓毒症存在器官功能障碍，还说明严重的代谢紊乱。研究显示，脓毒症患者高代谢、机体的营养需求增加，其营养状态与疾病进展、治疗和预后密切相关，对于该类患者的营养支持是我们研究的重点。既往多采用 Harris-Benedict公式评估患者的能量代谢，因脓毒症患者代谢紊乱，实际能量消耗与预测公式计算值存在偏差，据此对患者进行营养支持可能会造成营养不足或营养过度。间接测热法是测定患者能量消耗的“金标准”，其通过测定耗氧量、二氧化碳产生量以及静息能量消耗，反映机体的代谢状态，为脓毒症患者存在的代谢问题提供重要信息。本文综述间接测热法在脓毒症患者中的研究进展、未来应用与探索，讨论面临的挑战，旨在为患者的治疗和早期诊断提供方向。

关键词：脓毒症；能量代谢；间接测热法；机制

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