基于人工智能的新抗原预测研究进展
周雪侠

湖南工业大学 生物医学纳米材料与器件湖南省重点实验室，湖南省株洲市，412007；

摘要：癌症免疫治疗近年来在新抗原个性化疫苗和人工智能预测模型的应用中取得重大进展。肿瘤突变产生的新抗原能够激活T细胞免疫应答，为精准治疗提供了新的可能。然而，由于MHC的多态性及TCR识别机制的复杂性，新抗原的筛选仍然面临挑战。随着人工智能技术的引入，提高了新抗原预测的准确性和效率。

关键词：癌症免疫治疗；新抗原；个性化疫苗

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