白藜芦醇通过抗衰老防治阿尔茨海默病的作用与机制研究进展
赵珂璇 何玲^*

中国药科大学，江苏南京，211198；

摘要：白藜芦醇（Resveratrol, RSV）是一种天然多酚化合物，近年来在抗衰老和神经退行性疾病研究中备受关注。衰老被认为是阿尔茨海默病（AD）的主要风险因素，随着年龄的增长，神经元损伤、炎症反应和氧化应激等生理变化可能促进AD的发生。研究表明，白藜芦醇具有抗氧化、抗炎和神经保护特性，能够通过减少活性氧的产生、清除自由基以及激活SIRT1等途径，延缓衰老过程并改善AD病理。综上所述，白藜芦醇在抗衰老和神经保护方面的研究为理解衰老与神经退行性疾病之间的关系提供了新的视角，未来的研究有望进一步揭示其在AD治疗中的应用潜力。

关键词：白藜芦醇；衰老；阿尔兹海默症

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