中性粒细胞胞外诱捕网在转移性恶性胸腔积液中的表达及临床意义 

宋银丹 褚央映 陈捷 

余姚市人民医院检验科，浙江余姚，315400； 

摘要:目的：探讨中性粒细胞胞外诱捕网(NETs)在转移性恶性胸腔积液（MPE）中的表达及临床意义。方法：选取 良性和恶性胸腔积液患者各 40 例作为研究对象，对胸腔积液中的 NETs 主要标志物，即组织蛋白酶 G（CG）和髓 过氧化物酶（MPO）的含量进行了测定。结果：恶性胸腔积液患者的 CG 水平、MPO 的水平显著高于良性胸腔积液 组，两者之间的差异有统计学意义 ( P<0.01)。ROC 曲线分析中，CG、MPO 含量的测定对于转移性恶性胸腔积液 诊断具有较重要价值。结论 中性粒细胞胞外诱捕网（NETs）的检测在转移性恶性胸腔积液的诊断和鉴别诊断方 面具有一定的辅助临床价值。 

关键词:中性粒细胞胞外诱捕网；胸腔积液；组织蛋白酶 G；髓过氧化物酶(MPO) 

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基金项目:余姚市医疗卫生科技计划项目(2023YYB01)

作者简介:宋银丹（1983－），女，汉族，浙江余姚人，硕士，主治医师，主要从事临床检验学研究。