基于线粒体自噬探讨中医药干预阿尔茨海默病的研究进展 

王文芊 ¹ 王旭光 ² 

1 韶关学院医学院，广东韶关，512005； 

2 广东医科大学附属医院，广东湛江，524001； 

摘要：线粒体自噬在阿尔茨海默病（AD）的发生和发展中起着关键作用。通过促进线粒体自噬，可以增强神经保 护作用，并可能成为治疗阿尔茨海默病的新策略。近年来，传统中医药在阿尔茨海默病的干预中展现出独特的优 势，尤其是在调节线粒体自噬方面。中药成分通过多种机制影响线粒体功能，减轻神经元损伤，提供了新的治疗 思路。故将从中医药调节线粒体自噬，对线粒体自噬在 AD 中的作用机制和中医药对 AD 的调节方面进行综述，旨 在发现线粒体自噬和中医药在 AD 中参与的重要作用，为治疗 AD 提供理论依据和潜在方向。 

关键词：阿尔茨海默病；线粒体自噬；中医药 

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